Human biomonitoring initiative (HBM4EU) - Strategy to derive human biomonitoring guidance values (HBM-GVs) for health risk assessment
نویسندگان
چکیده
منابع مشابه
Interpreting human biomonitoring data in a public health risk context using Biomonitoring Equivalents.
Human biomonitoring (HBM) has proven an extremely valuable tool for determining which chemicals are getting into people, detecting trends in population exposures over time, and identifying populations with exposures above background. The potential significance of the HBM data in the context of existing toxicology data and risk assessments can be assessed if chemical-specific quantitative screen...
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Introduction Polychlorinated Biphenyls (PCBs) are persistent synthetic organochlorines. Due to their lipophilicity they accumulate in the food chain and in human lipid tissue and can cause a variety of dose-dependent adverse health effects in different tissues and organs. Although their prohibition in the early 1980ies led to a significant decrease of the body burden of the population, PCBs are...
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In her Postulate of 20 March 2008, National Councillor Moser (Green Liberal, Canton Zurich) requested the Federal Council to consider the introduction of systematic analysis of various groups of chemicals (pesticides, PCBs, UV filters, etc.) to which the Swiss population is exposed. In its response of 6 June 2008, the Federal Council stated that it was prepared to investigate how existing resea...
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Abstract A framework of "Common Criteria" (i.e. a series of questions) has been developed to inform the use and evaluation of biomonitoring data in the context of human exposure and risk assessment. The data-rich chemical benzene was selected for use in a case study to assess whether refinement of the Common Criteria framework was necessary, and to gain additional perspective on approaches fo...
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Bioethical principles are widely used as a normative framework in areas of human research and medical care. In recent years there has been increasing formalization of their use in public health decisions. The "traditional bioethical principles" are applied in this discussion to the important issue human biomonitoring for environmental exposures. They are: (1) Autonomy--Also known as the "respec...
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ژورنال
عنوان ژورنال: International Journal of Hygiene and Environmental Health
سال: 2020
ISSN: 1438-4639
DOI: 10.1016/j.ijheh.2020.113622